The absorption of gabapentin following high dose escalation

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چکیده

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The absorption of gabapentin following high dose escalation

Gabapentins (GBP) is structurally similar to GABA yet its mode of action remains uncertain. It is water-soluble and GI tract absorption occurs via the L-amino acid transport system in the proximal small bowel. It has been suggested that this transportation is capacity limited, thus decreasing GBP bioavailability at higher doses. GBP is not protein bound, therefore, salivary levels might be expe...

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ژورنال

عنوان ژورنال: Seizure

سال: 2003

ISSN: 1059-1311

DOI: 10.1016/s1059131102001425